First, enjoy this hi-resolution Binding of Isaac wallpaper. Second, come check out the game itself, a roguelike-Robotron-Zelda hybrid made by Team Meat, the guys who made Super Meat Boy. Basically, I think the idea is that you have to delve into randomly-generated Zelda 1 dungeons to defeat the horror that lurk within.
I've heard a lot about this game and I'm pretty pumped to play it. While I'm typing this up I'm buying it on steam and getting the DLC as well. For 8 dollars I'm sure it's going to be worth it.
I'll probably get some Steam trading cards out of this also...
Check it out now, LIVE at www.twitch.tv/Robot2600